進(jìn)口流感病毒A IgM 免疫診斷試劑盒

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進(jìn)口流感病毒A IgM 免疫診斷試劑盒

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【公司名稱】 廣州健侖生物科技有限公司
【市場部】     歐

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【騰訊  】 
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號二期2幢101-103室

組成蛋白質(zhì)的氨基酸有20種，根據(jù)密碼子擺動學(xué)說至少需要31種

tRNA,但在脊椎動物中只存在22種tRNA。1969年以來，研究了來

自各種不同生物：如酵母、大腸桿菌、小麥、鼠等十幾種tRNA的

結(jié)構(gòu)，證明它們的堿基序列都能折疊成三葉草形二級結(jié)構(gòu)（圖3-

23），而且都具有如下的共性：①5’末端具有G（大部分）或C。

②3’末端都以CCA的順序終結(jié)。③有一個(gè)富有鳥嘌呤的環(huán)。④有

一個(gè)反密碼子環(huán)，在這一環(huán)的頂端有三個(gè)暴露的堿基，稱為反密

碼子（anticodon）.反密碼子可以與mRNA鏈上互補(bǔ)的密碼子配對

。⑤有一個(gè)胸腺嘧啶環(huán)。又稱核糖體RNA（ribosomalRNA），

rRNA是組成核糖體的主要成分。核糖體是合成蛋白質(zhì)的工廠。在

大腸桿菌中，rRNA量占細(xì)胞總RNA量的75%-85%，而tRNA占15%，

mRNA僅占3-5%。rRNA一般與核糖體蛋白質(zhì)結(jié)合在一起，形成核糖

體（ribosome）。大腸桿菌核糖體的30S亞基由1分子沉降系數(shù)為

16S的rRNA和21個(gè)核糖體蛋白組成。50S亞基則由2個(gè)rRNA（23S

+5S）和34個(gè)核糖體蛋白組成。真核生物的核糖體更加復(fù)雜，由1

個(gè)以上的rRNA分子和更多的蛋白質(zhì)組成。如果把rRNA從核糖體上

除掉，核糖體的結(jié)構(gòu)就會發(fā)生塌陷。S為沉降系數(shù)

（sedimentationcoefficient），當(dāng)用超速離心測定一個(gè)粒子

的沉淀速度時(shí)，此速度與粒子的大小直徑成比例。5S含有120個(gè)核

苷酸，16S含有1540個(gè)核苷酸，而23S含有2900個(gè)核苷酸。而真核

生物有4種rRNA，它們分子大小分別是5S、5.8S、18S和28S，分

別具有大約120、160、1900和4700個(gè)核苷酸。rRNA是單鏈，它包

含不等量的A與U、G與C，但是有廣泛的雙鏈區(qū)域。在雙鏈區(qū)，堿

基因氫鍵相連，表現(xiàn)為發(fā)夾式螺旋。rRNA在蛋白質(zhì)合成中的功能

尚未*明了。但16S的rRNA3’端有一段核苷酸序列與mRNA的前

導(dǎo)序列是互補(bǔ)的，這可能有助于mRNA與核糖體的結(jié)合。調(diào)控功能

的非編碼RNA，其大小長約20~25個(gè)核苷酸。成熟的miRNAs是由較

長的初級轉(zhuǎn)錄物經(jīng)過一系列核酸酶的剪切加工而產(chǎn)生的，隨后組

裝進(jìn)RNA誘導(dǎo)的沉默復(fù)合體，通過堿基互補(bǔ)配對的方式識別靶mRNA

，并根據(jù)互補(bǔ)程度的不同指導(dǎo)沉默復(fù)合體降解靶mRNA或者阻遏靶

mRNA。

There are 20 kinds of amino acids that make up the protein, and at least 31 species are required according to the codon swing theory

tRNA, but there are only 22 tRNAs in vertebrates. Since 1969, studied

Since a variety of different organisms: such as yeast, E. coli, wheat, mice and a dozen tRNA

Structure, to prove that their base sequence can be folded into clover-shaped secondary structure (Figure 3-

23), and all have the following common features: ① 5 'end with G (most) or C.

② 3 'end of the order to end in CCA. ③ have a guanine ring. ④ there

An anticodon loop, with three exposed bases at the top of the loop, called backflush

The anticodon can pair with complementary codons on the mRNA strand

. ⑤ There is a thymine ring. Also known as ribosomal RNA,

rRNA is the main component of ribosomes. Ribosomes are factories that synthesize proteins. in

In E. coli, rRNA accounts for 75% -85% of total cellular RNA, while tRNA accounts for 15%

mRNA only accounts for 3-5%. RRNAs are typically associated with ribosomal proteins to form ribose

The ribosome. The 30S subunit of E. coli ribosomes has a sedimentation coefficient of 1 molecule

16S rRNA and 21 ribosomal proteins. The 50S subunit consists of two rRNAs (23S

+ 5S) and 34 ribosomal proteins. Eukaryotic ribosomes are more complicated by

More than one rRNA molecule and more proteins. If rRNA from the ribosome

Removed, the ribosome structure collapse occurs. S is the sedimentation coefficient

Sedimentationcoefficient, when one particle is measured by ultracentrifugation

Of the precipitation speed, the speed and the size of the particle diameter proportional to. 5S contains 120 nuclei

The nucleotide, 16S contains 1540 nucleotides, whereas 23S contains 2900 nucleotides. And eukaryotic

There are 4 rRNA organisms, their molecular size is 5S, 5.8S, 18S and 28S, respectively

Do not have about 120, 160, 1900 and 4700 nucleotides. rRNA is single-stranded, it's package

There are unequal amounts of A and U, G and C, but a wide range of double-stranded regions. In the double-stranded region, alkali

Gene hydrogen bonds, the performance of hairpin spiral. The function of rRNA in protein synthesis

Not yet fully understood. However, the 16S rRNA3 'end has a nucleotide sequence that precedes the mRNA

The leader sequence is complementary, which may contribute to the binding of mRNA to ribosomes. Regulatory functions

Of non-coding RNA, the size of about 20 to 25 nucleotides in length. Mature miRNAs are compared

Long primary transcripts are produced by a series of nuclease cleavage processes, followed by the grouping

Into the RNA-induced silencing complex, the target mRNA is recognized by base-pairing

, And depending on the degree of complementarity, silence the silencing complex to direct the target mRNA or repress the target

Translation of mRNA.