S-100鈣結(jié)合蛋白P(S-100)重組蛋白

廣州健侖生物科技有限公司

S100蛋白是一組具有EF-手形的鈣依賴調(diào)節(jié)蛋白，參與一系列細(xì)胞內(nèi)活動(dòng)的調(diào)節(jié)，包括細(xì)胞增殖/分化、蛋白質(zhì)磷酸化、酶活性、細(xì)胞內(nèi)鈣穩(wěn)態(tài)和轉(zhuǎn)錄因子活性等；S100家族成員的基因表達(dá)異常也與大多數(shù)人類腫瘤相關(guān)。S-100蛋白有3種亞型：S-100ao、S-100a、S-100b，主要存在神經(jīng)組織、垂體、頸動(dòng)脈體、腎上腺髓質(zhì)、唾液腺和少數(shù)間葉組織中。主要用于星形膠質(zhì)瘤、室管膜瘤、神經(jīng)母細(xì)胞瘤、神經(jīng)鞘瘤、惡黑、脂肪肉瘤和Langerhans細(xì)胞增生疾病的研究。

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S-100鈣結(jié)合蛋白P(S-100)重組蛋白

【產(chǎn)品介紹】

細(xì)胞定位：細(xì)胞漿/細(xì)胞核

克隆號：16/f5

同型：IgG

適用組織：石蠟/冰凍

陽性對照：胎盤/胰腺導(dǎo)管癌

抗原修復(fù)：熱修復(fù)（EDTA）

抗體孵育時(shí)間：30-60min

S-100鈣結(jié)合蛋白P(S-100)重組蛋白

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【公司名稱】 廣州健侖生物科技有限公司
【市場部】     歐

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【騰訊  】 
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號二期2幢101-103室

對從病人機(jī)體分離的肝臟及抗原抗體腫瘤組織進(jìn)行分析，研究者發(fā)現(xiàn)，癌癥中ASPP2表達(dá)的欠缺和病人較低的生存率直接相關(guān);蛋白ASPP2可以通過和E-鈣粘蛋白及β-連環(huán)蛋白的關(guān)聯(lián)來控制MET和EMT過程。zui后研究者Lu表示，近些年來我們已經(jīng)對驅(qū)動(dòng)EMT的過程研究地非常多了，但是對于MET過程的發(fā)生卻知之甚少，而MET過程對于機(jī)體的健康及癌癥的轉(zhuǎn)移又至關(guān)重要，而本文的zui大亮點(diǎn)就是我們鑒別出了MET的誘導(dǎo)子及守護(hù)者，這對于后期開發(fā)治療癌癥的新型靶向療法提供了新的研究思路和依據(jù)。
日本東京大學(xué)教授竹內(nèi)昌治率領(lǐng)的研究小組24日宣布，通過把人工培養(yǎng)的肌肉組織安在人工關(guān)節(jié)上，他們成功制作出了能像人類手指那樣屈伸的人工手指。這一成果有望在再生醫(yī)療領(lǐng)域得到應(yīng)用。
研究人員將大鼠的肌肉細(xì)胞植入特殊的凝膠層，然后將多個(gè)凝膠層放在一起進(jìn)行培養(yǎng)，zui終培養(yǎng)出了長約8毫米、厚約1.5毫米的立體肌肉組織。
隨后，研究人員在長2厘米的塑料棒兩側(cè)分別安裝了人工培養(yǎng)出的大鼠肌肉組織，塑料棒正中安裝有關(guān)節(jié)。利用微弱的電流進(jìn)行刺激后，肌肉就會(huì)收縮，而輪流刺激兩側(cè)的肌肉，就能使塑料棒像手指那樣屈伸。

Analysis of the liver and antigen-antibody-tumor tissue isolated from the patient's body revealed that the lack of ASPP2 expression in cancer was directly linked to the lower survival rate of the patient; the protein ASPP2 was directly linked to E-cadherin and β-catenin To control the MET and EMT processes. Last researcher Lu said that in recent years we have studied very much about the EMT driving process but have little knowledge of the occurrence of MET events that are crucial for the health of the body and the transfer of cancer, The highlight of this article is that we identified the elicitors and guardians of MET, which provided a new research idea and basis for the later development of new targeted therapies for the treatment of cancer.
A team led by Professor Takeuchi Masaharu of the University of Tokyo in Japan announced on the 24th that they successfully produced artificial fingers that flexed like human fingers by putting artificial muscle tissue in artificial joints. This result is expected to be applied in the field of regenerative medicine.
Researchers planted muscle cells from rats into a special gel layer and then placed multiple gel layers together to create a three-dimensional muscle tissue approximay 8 mm long and 1.5 mm thick.
Subsequently, the researchers in the 2 cm long plastic rods installed on both sides of the artificial culture of rat muscle tissue, plastic rods installed in the middle section. When stimulated with a weak electric current, the muscles contract, and in turn, stimulate the muscles on either side, making the plastic rod bend like a finger.